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Thrombocytopenia and detection of cytoplasm fragments from monoblasts

Thrombocytopenia and detection of cytoplasm fragments from monoblasts

Thrombocytopenia and detection of cytoplasm fragments from monoblasts in AML-M5A. Due to their similar size the cytoplasm fragments can produce a falsely elevated platelet count in impedance measurement on certain haematology analysers. Here the initial count was 32,000/μL. The correct platelet value was obtained from the optical channel; it was 7,000/μL. Cytoplasm fragments (C) and a platelet (P) are marked.

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