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'Rouleaux formation' of red blood cells

'Rouleaux formation' of red blood cells

In peripheral blood of a patient with multiple myeloma (May-Grünwald-Giemsa stain) no plasma cells are detectable, because in multiple myeloma these are only rarely found in the periphery. The monoclonal immunoglobulin causes an increased erythrocyte sedimentation rate (ESR) and 'rouleaux formation' (->) of red blood cells.