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Peripheral blood of a patient with B-CLL

Peripheral blood of a patient with B-CLL

Peripheral blood (May-Grünwald-Giemsa stain) of a patient with B-CLL. The few platelets are mostly large (->) (= platelet anisocytosis). Here a secondary immune thrombocytopenia (ITP) was evoked by immunoglobulin-producing lymphoma cells. The immunoglobulins react with proteins on the platelet surface, leading to an elimination of these platelets from the peripheral blood.