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Increase of all three cell lineages in peripheral blood of a patient with PV

Increase of all three cell lineages in peripheral blood of a patient with PV

In the peripheral blood (May-Grünwald-Giemsa stain) of this 75-year old woman with PV all three cell lineages are increased: haemoglobin concentration 16 g/dL, white blood cell count 15,000/µL, platelet count 980,000/µL. In functional iron deficiency red blood cells often are microcytic. The MCV is only 75 fL. The haematopoietic cells of the patient show a JAK2 mutation.