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Hodgkin cells

Hodgkin cells

Bone marrow histology (Giemsa stain) showing two Hodgkin cells (H). These giant cells have an oval, non-lobulated nucleus and at least one nucleolus. Reed-Sternberg cells (RS) have a lobulated nucleus with several nucleoli. Both cell types are characteristic of Hodgkin's disease and express the same surface marker CD30, which is otherwise found on activated lymphocytes.