FIT screening

The FIT-based screening test is easy and therefore manages to attract high participation rates – the main driver behind the success of any national or regional screening programme. Generally, national or regional administrations assume responsibility for managing the logistics, financials and efficiency of the programme in close cooperation with their selected laboratory partners.

For further information, you can check our FIT for screening microsite. 
www.fitscreening.eu/

 

 

Viscotek TDAmax

  • Comprehensive characterization of all types of macromolecules - proteins, natural polymers and synthetic polymers
  • Absolute molecular weight using Low Angle Light Scattering (LALS) or Right Angle Light Scattering (RALS)
  • High-sensitivity Viscometer detector for intrinsic viscosity and structural information such as polymer branching
  • Molecular size information as hydrodynamic radius (down to <1nm) and radius of gyration
  • Copolymer, conjugates and blends can be fully characterized with the optional UV detector

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A complete, temperature controlled, RI, Viscometer, Light Scattering, triple-detector GPC/SEC system

The Viscotek TDAmax is a complete stand-alone, research grade, temperature controlled, multi-detector GPC/SEC system suitable for the molecular weight and molecular size determination of proteins, natural and synthetic polymers, copolymers and other macromolecules.

Configuration
The TDAmax consists of three components – the GPCmax integrated solvent and sample delivery module, the TDA 305 Triple Detector Array, and the OmniSEC software. The TDA 305 incorporates RI and, Light Scattering detectors, as well as a viscometer and optional UV detector. Both the integrated detectors and the chromatography columns are fully temperature controlled in an oven to ensure optimum detector stability. In addition, the detectors are connected in series to ensure maximum sensitivity.

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Specifications

Specifications

System
System: GPCmax
Pump flow rate: 0.01 to 9.99 mL/min, programmable soft start
Pulsation: Less than 1%, measured with viscometer
Degasser: Two channels, < 0.5ppm oxygen at ) 0.5mL/min, eluent sensor to stop pump when eluent runs out
Dimensions (W, D, H):55cm x 53cm x 38cm
Weight: 37kg
Software: OmniSEC, 6 channels at 5Hz, unlimited acquisition time

Autosampler
Capacity:120 vials, programmable sequence
Injection volume: Variable 20 to 150µL
Reproducibility: Better than 0.5%
Carryover: Less than 0.1%, depending on wash program
Cooling option: 4°C to 40°C, limited to 60 vials
Heated tray option: Up to 65°C limited to 60 vials heated, 60 vials unheated

TDAmax
Detector: TDAmax
Temperature range: Ambient to 80°C, all detector cells and columns
Column capacity: Up to 5 x 30cm columns
Interface: 6 channel digital to OmniSEC software, 2 analogue inputs RI and UV/LS
Dimensions (W, D, H):41cm x 54cm x 28cm
Weight: 30kg

Detector 1
Detector: Light scattering
Measurement principle: RALS 90° angle, LALS 7° angle
Light source: 3mW laser diode, 670nm, temperature controlled
Cell volume: 18µL
Data acquisition rate: 100Hz collection, 5Hz to OmniSEC

Detector 2
Detector: Refractive index
Measurement principle: Deflection
Light source: LED
Cell volume: 12µL
Data acquisition rate: 100Hz collection, 5Hz to OmniSEC

Detector 3
Detector: Viscometer
Measurement principle: 4 capillary differential Wheatstone bridge configuration
Transducers: Digital Inert Transducers with over-pressure protection
Cell volume: 18µL
Data acquisition rate: 100Hz collection, 5Hz to OmniSEC

Detector 4 (option)
Detector: UV, Single wavelength programmable
Wavelength:190 to 500nm
Light source: Deuterium 
Cell volume: 10µL
Data acquisition rate: Analog, A-to-D with 5Hz to OmniSEC
Operating environment
Temperature:15°C - 40°C
Humidity: 35% - 80% non-condensing

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