Sysmex Nederland

Malvern Zetasizer Nano Z

  • Zeta potential using patented M3-PALS technology
  • 21CFR part 11 software option to enable compliance with ER/ES
  • A ‘Quality Factor’ and ‘Expert Advice System’ gives the confidence of having an expert at your shoulder.
  • Research software option to give access to further features and analysis algorithms for the light scattering specialist.


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Dedicated zeta potential analyzer

The Zetasizer Nano Z system is dedicated to the measurement of zeta potential and electrophoretic mobility in aqueous and non-aqueous dispersions using Laser Doppler Micro-Electrophoresis. The Zetasizer Nano Z is the perfect system for measuring zeta potential and electrophoretic mobility of colloids and nanoparticles, when the measurement of size or molecular weight is not required.

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Measurement type
Zeta potential

Measurement range
3.8nm - 100 microns* (diameter)

Measurement principle
Electrophoretic Light Scattering

Minimum sample volume
150µL (20µL using diffusion barrier method)

0.12µ for aqueous systems using NIST SRM1980 standard reference material.

10mg/mL (BSA)

Temperature control range
0°C - 90°C +/-0.1**, 120°C option.

Light source
He-Ne laser 633nm, Max 4mW.

Laser safety
Class 1

320 (W) x 600 (D) x 260 (H) mm

21 kg

How it works

How it works

The Zetasizer Nano Z uses micro-electrophoresis / electrophoretic light scattering technology to measure zeta potential and electrophoretic mobility.

Laser Doppler Micro-electrophoresis is used to measure zeta potential. An electric field is applied to a solution of molecules or a dispersion of particles, which then move with a velocity related to their zeta potential. This velocity is measured using a patented laser interferometric technique called M3-PALS (Phase analysis Light Scattering). This enables the calculation of electrophoretic mobility, and from this, the zeta potential and zeta potential distribution.

The software is designed to be versatile and rich in features without compromising ease of use. Standard Operating Procedures (SOP) simplify routine measurements, a quality factor gives a single place for confirmation of data quality, and an expert advice system is provided to assist with data interpretation.

The MPT-2 Autotitrator enables the study of the effect of changes in pH, conductivity, or any additive to be automated.

A range of disposable and reusable cells are available to optimize the measurement in terms of sample volume, concentration and flow measurement.

Other options include filters to improve the measurement of fluorescent samples, a temperature range extension to 120ºC and a viscometer to determine the sample viscosity to the accuracy required for the techniques used.



A cost effective accessory designed to automate the measurement of size and zeta potential as a function of pH, conductivity or any soluble additive.SV-10 viscometerThe SV-10 measures viscosity with the accuracy required for dynamic light scattering, for the conversion of diffusion speed to size, and electrophoretic mobility to zeta potential, in an extremely simple and rapid system.

Disposable folded capillary cell (DTS1070)
The zeta potential of colloids and molecules is extremely sensitive to contamination from components of a previous sample used in a measurement cell. The use of a disposable cell completely eliminates this potential contamination issue.The folded capillary cell provides the benefits of the accuracy of measurement of a capillary cell with the ease of use of a disposable cell.Although, disposable, including the electrodes, for low conductivity samples each cell can be used for hundreds of measurements if required.The cell can be used with the autotitrator, where multiple measurements are routinely done over a wide pH range.

Universal 'dip' cell kit
The dip cell is used for the measurement of zeta potential of samples in aqueous and non-aqueous dispersants, and is designed to be cleaned and reused. It is for batch measurements using standard polystyrene or glass cuvettes.

High concentration zeta potential cell kit
The high concentration cell enables the measurement of the zeta potential of samples with little or no dilution in any Zetasizer Nano system that measures zeta potential.The cell has a flow configuration so can be used for stop-flow size and zeta potential measurements using an MPT-2 autotitrator as well as batch measurements.

Surface zeta potential accessory
The characterization of surfaces and interfaces is critical in a wide range of industries including consumer products, specialty chemicals, pharmaceuticals and life sciences. In each of these application areas, the interaction of molecules and particles with surfaces can influence the material properties of the end product.The surface zeta potential accessory enables the measurement of the zeta potential of flat surfaces such as filter paper, silica, polymers and bone, using a standard Zetasizer Nano system.

Quartz flow cell (ZEN0023)
Add flow capability for size measurements to the Zetasizer.

12mm Glass cell (PCS1115)
Glass cuvette for use with the dip cell.

50mW 532nm DPSS laser
For use where the sample is incompatible with the standard 633nm laser, either because the sample absorbs or fluoresces, or the sample is photosensitive.

Narrow band filters
Useful where the sample fluoresces. Eliminates scattering due to fluorescence to improve the signal to background ratio.

High temperature capability
Increases the high temperature capability from 90°C to 120°C. Suitable for samples in wax media that melt above 90°C.

Degasser for MPT-2 autotitrator
Titrants used by the MPT-2 titrator need regular degassing, ideally before each titration.Degassing is required to remove bubbles that can affect the volume of titrant dispensed. This is particularly important close to pH 7 where low volumes of titrant are required.



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