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Malvern NanoSight NS300

  • Simultaneous measurement of multiple characteristics, saving time and sample volume
  • Visual validation of results gives extra confidence
  • Minimal sample preparation
  • On board temperature control
  • Choice of laser wavelengths and up to 6 different filters in a motorized wheel provides flexible fluorescence detection capability

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Optimized for fluorescence work

The Malvern NanoSight NS300 Instrument provides an easy-to-use, reproducible platform for nanoparticle characterization.

The NS300 allows rapid, automated analysis of the size distribution and concentration of all types of nanoparticles from 10nm to 2000nm in diameter, depending on the instrument configuration and sample type.

With the ability to be supplied with interchangeable laser modules and theintroduction of a motorized 6 place filter wheel means different fluorescent labels can be analyzed. Sample temperature is fully programmable through the Nanoparticle Tracking Analysis (NTA) software.

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Specifications

Specifications

Wavelength
405nm (violet), 488nm (blue), 532nm (green) or 642nm (red)

Temperature control range
5°C below ambient to 50°C

Stage
Fixed stage

Focus
Computer controlled motorized focus

Camera
sCMOS

Fluorescence
Motorized 6 place filter wheel with choice of filters

Dimensions
400 (W) x 250 (D) x 400 (H) mm

Particle size
10nm to 2000nm

Concentration range
106 to 109 particles per mL

How it works

How it works

The Malvern Panalytical NanoSight NS300 uses the technology of Nanoparticle Tracking Analysis (NTA). This unique technology utilizes the properties of both light scattering and Brownian motion in order to obtain the size distribution and concentration measurement of particles in liquid suspension. A laser beam is passed through the sample chamber, and the particles in suspension in the path of this beam scatter light in such a manner that they can easily be visualized via 20x magnification microscope onto which is mounted a camera. The camera operates at 30 frames per second (fps), capturing a video file of the particles moving under Brownian motion. The software tracks many particles individually and using the Stokes-Einstein equation calculates their hydrodynamic diameters.

Accessories

Accessories

NanoSight Sample Assistant
The NanoSight Sample Assistant is a 96-well plate-based autosampler accessory with a bespoke software suite for SOP generation via an intuitive user interface for automated NTA measurements.

NanoSight syringe pump
The Malvern Panalytical NanoSight syringe pump is available for all Malvern Panalytical NanoSight systems, enabling users to perform sample analysis at a constant flow rate.

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