Sysmex Nederland

Jo Linssen receives award from Japanese Royal Family Member

Joachim Linssen from Sysmex Europe, Yoshiro Ikeuchi, Shinichiro Oguni, Daigo Fukuma, and Masanori Imazu have been awarded the Invention Award in the National Commendation for Invention, sponsored by the Japan Institute of Invention and Innovation. Their contribution? A blood test that makes it possible to quickly evaluate the effects of administering iron preparations.

Date: 2017-08-25 Tags: News, Netherlands, Belgium

The award ceremony was held in the traditional Japanese Hotel Okura in Tokyo on Monday, 12 June 2017, and was attended by Prince Masahito Hitachi, a member of the Japanese royal family. Prince Masahito is also the President of the Japan Institute of Invention and Innovation

The National Commendation for Invention was established in 1919 to contribute to the advancement of Japanese technology and the development of industry. Since then, the award has been presented to recognise distinguished achievements in invention and design, and for innovations that are believed to have a strong potential for significant future success.

The Invention Award presented recently was for a blood test that enables the 'Rapid Evaluation of the Effects of Administering Iron Preparations', which in turn contributes to quickly defining treatment methods for renal anaemia (dialysis patients). Among patients with chronic kidney disease, particularly those with renal anaemia caused by complications from dialysis, anaemia can be traced to reduced kidney function. This reduced function causes a decrease in the capacity to secrete the hormone erythropoietin, which stimulates the production of red blood cells. A prevalent treatment method involves administering erythropoiesis stimulating agents (ESAs) and iron to stimulate red blood cell production. However, the over-administration of iron can produce side effects. To prevent such over-administration, it is important to quickly evaluate how the administered iron affects red blood cell production.

To quickly evaluate the effect of iron administration, the test calculates the reticulocyte haemoglobin equivalent (RET-He). Reticulocytes are cells at the stage prior to red blood cell maturation. With this invention, cell groups of reticulocytes are classified based on the scattered light caused when biological blood specimens are irradiated with light. The average value of the scattering intensity of reticulocytes contained in the cell groups is obtained, and this value is used to determine the volume of RET-He.

Knowing the effects of administering iron preparations can help prevent its over-administration. Such evaluation is also useful in evaluating ESA administration, thereby preventing more ESA than necessary being administered and reducing healthcare costs.

Congratulations Jo! We're looking forward to more!

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